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CD4+ Memory Stem T Cells Recognizing Citrullinated Epitopes Are Expanded in Patients With Rheumatoid Arthritis and Sensitive to Tumor Necrosis Factor Blockade.
Arthritis & Rheumatology ( IF 13.3 ) Pub Date : 2020-03-05 , DOI: 10.1002/art.41157 Beatrice C Cianciotti 1 , Eliana Ruggiero 2 , Corrado Campochiaro 1 , Giacomo Oliveira 2 , Zulma I Magnani 2 , Mattia Baldini 2 , Matteo Doglio 2 , Michela Tassara 2 , Angelo A Manfredi 1 , Elena Baldissera 2 , Fabio Ciceri 1 , Nicoletta Cieri 2 , Chiara Bonini 1
Arthritis & Rheumatology ( IF 13.3 ) Pub Date : 2020-03-05 , DOI: 10.1002/art.41157 Beatrice C Cianciotti 1 , Eliana Ruggiero 2 , Corrado Campochiaro 1 , Giacomo Oliveira 2 , Zulma I Magnani 2 , Mattia Baldini 2 , Matteo Doglio 2 , Michela Tassara 2 , Angelo A Manfredi 1 , Elena Baldissera 2 , Fabio Ciceri 1 , Nicoletta Cieri 2 , Chiara Bonini 1
Affiliation
Memory stem T (Tscm) cells are long‐lived, self‐renewing T cells that play a relevant role in immunologic memory. This study was undertaken to investigate whether Tscm cells accumulate in rheumatoid arthritis (RA).
中文翻译：
类风湿性关节炎患者中识别瓜氨酸表位的CD4 +记忆干T细胞扩增，对肿瘤坏死因子阻断敏感。
记忆干T（Tscm）细胞是长寿的，自我更新的T细胞，在免疫记忆中起着重要的作用。进行这项研究以调查Tscm细胞是否在类风湿关节炎（RA）中积聚。
更新日期：2020-04-22
中文翻译：
类风湿性关节炎患者中识别瓜氨酸表位的CD4 +记忆干T细胞扩增，对肿瘤坏死因子阻断敏感。
记忆干T（Tscm）细胞是长寿的，自我更新的T细胞，在免疫记忆中起着重要的作用。进行这项研究以调查Tscm细胞是否在类风湿关节炎（RA）中积聚。
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