Practical aspects of the oligopeptide AAKLVFF as an alignment medium are discussed, including large‐scale synthesis of the oligopeptide, detailed description of preparation of the alignment medium, and acquisition of the RDCs. The resulting orienting medium is stable and highly homogeneous with tunable alignment strength in methanol. We demonstrated its applicability on the stereochemical elucidation of two natural products, oridonin and α‐santonin.

中文翻译：

---

寡肽 AAKLVFF 作为对准介质用于测量有机分子的残余偶极耦合的实际方面

讨论了寡肽 AAKLVFF 作为对齐介质的实际应用，包括寡肽的大规模合成、对齐介质制备的详细描述以及 RDC 的获取。所得定向介质稳定且高度均匀，在甲醇中具有可调的取向强度。我们证明了其适用于两种天然产物冬凌草甲素和α-山东宁的立体化学解析。