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3D magnetopneumography magnetic dipole model and its application using fluxgate gradiometers.
Bioelectromagnetics ( IF 1.9 ) Pub Date : 2019-09-08 , DOI: 10.1002/bem.22216 Yunlong Fang 1, 2
Bioelectromagnetics ( IF 1.9 ) Pub Date : 2019-09-08 , DOI: 10.1002/bem.22216 Yunlong Fang 1, 2
Affiliation
Magnetopneumography (MPG) as a non-invasive method for pneumoconiosis diagnosis has been developed to evaluate the load and spatial distribution of particles within the human lungs through scanning of remanent magnetic fields after magnetization of the subject in a strong direct current field. The measurement of particle spatial distribution is very important for pneumoconiosis diagnosis because localized deposits may be associated with some pathological changes such as pulmonary fibrosis. Previous research found that loads of magnetite particles were proportional to their magnetic dipole moments. The three-dimensional (3D) MPG magnetic dipole model (MDM) proposed in this paper and based on Biot-Savart Law and matrix manipulation provides a means of precise measurement of the particle distribution and load amount. A styrofoam + magnetite powder phantom with magnetization was laid on a nonmagnetic board. Two first-order fluxgate gradiometers with 10-12 T sensitivity were coaxially applied over and under the phantom and used for scanning remanent magnetic fields. This paper provides validation results using 3D MPG MDM through two experiments. The overall error of the simulation results is 0.2-2.7% in the center and 7.28-9.42% in the corners of the subject. Finally, this paper gives clinical experiments with a welder suffering stage-II pneumoconiosis and states that the 3D MPG MDM shows similar results to X-ray chest films in pneumoconiosis diagnosis. The results suggest that the 3D MPG MDM is potentially a reasonable and accurate algorithmic model to inversely track the load amount and distribution of magnetite particles within the lungs. Bioelectromagnetics. 2019;40:472-487. © 2019 Wiley Periodicals, Inc.
中文翻译:
使用磁通门梯度仪的3D磁气波照相术磁偶极子模型及其应用。
已经开发出磁尘肺病(MPG)作为尘肺病诊断的一种非侵入性方法,通过在强直流电中对受试者进行磁化后,通过扫描剩余磁场来评估人肺内颗粒的负荷和空间分布。颗粒空间分布的测量对于尘肺病的诊断非常重要,因为局部沉积物可能与某些病理变化(例如肺纤维化)有关。先前的研究发现,磁铁矿颗粒的载荷与其磁偶极矩成正比。本文提出的三维(3D)MPG磁偶极子模型(MDM)是基于Biot-Savart定律和矩阵处理的,它提供了一种精确测量粒子分布和负载量的方法。将具有磁化作用的聚苯乙烯泡沫塑料+磁铁矿粉体模放在非磁性板上。将两个灵敏度为10-12 T的一阶磁通门梯度仪同轴放置在体模的上方和下方,并用于扫描剩余磁场。本文通过两个实验提供了使用3D MPG MDM的验证结果。模拟结果的总体误差在对象的中心为0.2-2.7%,在角落为7.28-9.42%。最后,本文提供了患有II级尘肺的焊工的临床实验,并指出3D MPG MDM在尘肺的诊断中显示出与X线胸片相似的结果。结果表明,3D MPG MDM可能是一种合理,准确的算法模型,可以反向跟踪肺内磁铁矿颗粒的负荷量和分布。生物电磁学。2019; 40:472-487。分级为4 +©2019 Wiley Periodicals,Inc.
更新日期:2019-09-08
中文翻译:
使用磁通门梯度仪的3D磁气波照相术磁偶极子模型及其应用。
已经开发出磁尘肺病(MPG)作为尘肺病诊断的一种非侵入性方法,通过在强直流电中对受试者进行磁化后,通过扫描剩余磁场来评估人肺内颗粒的负荷和空间分布。颗粒空间分布的测量对于尘肺病的诊断非常重要,因为局部沉积物可能与某些病理变化(例如肺纤维化)有关。先前的研究发现,磁铁矿颗粒的载荷与其磁偶极矩成正比。本文提出的三维(3D)MPG磁偶极子模型(MDM)是基于Biot-Savart定律和矩阵处理的,它提供了一种精确测量粒子分布和负载量的方法。将具有磁化作用的聚苯乙烯泡沫塑料+磁铁矿粉体模放在非磁性板上。将两个灵敏度为10-12 T的一阶磁通门梯度仪同轴放置在体模的上方和下方,并用于扫描剩余磁场。本文通过两个实验提供了使用3D MPG MDM的验证结果。模拟结果的总体误差在对象的中心为0.2-2.7%,在角落为7.28-9.42%。最后,本文提供了患有II级尘肺的焊工的临床实验,并指出3D MPG MDM在尘肺的诊断中显示出与X线胸片相似的结果。结果表明,3D MPG MDM可能是一种合理,准确的算法模型,可以反向跟踪肺内磁铁矿颗粒的负荷量和分布。生物电磁学。2019; 40:472-487。分级为4 +©2019 Wiley Periodicals,Inc.