Detection of pesticide residues in food samples is important for safeguarding food quality and safety. Conventional approaches for detection of pesticides in food samples typically involve labour-intensive and time-consuming sample pretreatment and chromatographic separation. In this study, solid phase micro-extraction fibres were used to rapidly extract and enrich pesticides in honey, a popular agricultural product with complex matrix, and then directly coupled with electrospray ionization mass spectrometry for qualitative and quantitative analysis. Three pesticides, ie, atrazine, benalaxyl, and pirimicarb, were investigated using the technique and their analytical performances were evaluated. The limits of detection and limits of quantitation of all the three pesticides could fulfil the cut-off values of the international standard. Linear calibration curves were constructed with good R2 coefficients, and the accuracy and precision were in acceptable ranges for all the pesticides. The analysis time is much reduced, with only minimum sample preparation and no chromatographic separation involved. The technique is simple and easy to set up, and can be extended for analysis of other analytes and sample systems.

中文翻译：

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固相微萃取结合电喷雾电离质谱法快速检测蜂蜜中的农药。

食品样品中农药残留的检测对于维护食品质量和安全非常重要。检测食品样品中农药的常规方法通常涉及劳动强度大，耗时的样品预处理和色谱分离。在这项研究中，固相微萃取纤维用于快速提取和富集蜂蜜（一种具有复杂基质的受欢迎的农产品）中的农药，然后直接与电喷雾电离质谱联用进行定性和定量分析。利用该技术研究了阿特拉津，苯那西林和吡虫威这三种农药，并对其分析性能进行了评估。这三种农药的检出限和定量限可以满足国际标准的临界值。线性校正曲线具有良好的R2系数，所有农药的准确度和精密度均在可接受的范围内。分析时间大大减少，仅需最少的样品制备，无需色谱分离。该技术简单易行，可以扩展用于分析其他分析物和样品系统。