In the Special Issue on Tools for Protein Science in 2018, we presented Molstack: a concept of a cloud-based platform for sharing electron density maps and their interpretations. Molstack is a web platform that allows the interactive visualization of density maps through the simultaneous presentation of multiple datasets and models in a way that allows for easy pairwise comparison. We anticipated that the users of this conceptually simple platform would find many different uses for their projects, and we were not mistaken. We have observed researchers use Molstack to present experimental evidence for their models in the form of electron density maps, omit maps, and anomalous difference density maps. Users also employed Molstack to present alternative interpretations of densities, including rerefinements and speculative interpretations. While we anticipated these types of projects to be the main use cases, we were pleased to see Molstack used to display superpositions of different models, as a tool for story-driven presentations, and for collaboration as well. Here, we present developments in the platform that were driven by user feedback, highlight several cases that used Molstack to enhance the publication, and discuss possible directions for the platform.

中文翻译：

---

Molstack：一个用于交互式演示电子密度和低温电磁图及其解释的平台。

在2018年蛋白质科学工具特刊中，我们介绍了Molstack：基于云的平台的概念，用于共享电子密度图及其解释。Molstack是一个Web平台，它允许通过同时呈现多个数据集和模型的方式方便地进行成对比较，从而以交互方式可视化密度图。我们期望这个概念上简单的平台的用户会在他们的项目中发现许多不同的用途，并且我们没有弄错。我们已经观察到研究人员使用Molstack以电子密度图，省略图和反常差异密度图的形式为他们的模型提供实验证据。用户还使用Molstack来介绍密度的其他解释，包括改进和推测性解释。尽管我们预计这些类型的项目将是主要的用例，但我们很高兴看到Molstack用来显示不同模型的叠加，用作故事驱动的演示文稿以及进行协作的工具。在这里，我们介绍了平台上受用户反馈驱动的开发情况，重点介绍了使用Molstack增强出版物的几种情况，并讨论了平台的可能方向。