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Serotonin Prevents Differentiation of Brown Adipocytes by Interfering with Their Clock.
Obesity ( IF 6.9 ) Pub Date : 2019-11-01 , DOI: 10.1002/oby.22606 Sigal Rozenblit-Susan 1 , Nava Chapnik 1 , Oren Froy 1
Obesity ( IF 6.9 ) Pub Date : 2019-11-01 , DOI: 10.1002/oby.22606 Sigal Rozenblit-Susan 1 , Nava Chapnik 1 , Oren Froy 1
Affiliation
Serotonin was shown to interfere with the differentiation of brown adipocytes. In addition, clock components inhibit brown adipogenesis through direct transcriptional control of key components of the transforming growth factor β pathway. The aim of this study was to investigate whether serotonin abrogates brown adipogenesis by affecting clock functionality.
中文翻译:
血清素通过干扰时钟来防止棕色脂肪细胞的分化。
显示5-羟色胺会干扰棕色脂肪细胞的分化。另外,时钟成分通过直接转录控制转化生长因子β途径的关键成分来抑制褐色脂肪形成。这项研究的目的是研究5-羟色胺是否通过影响时钟功能来消除褐色脂肪形成。
更新日期:2019-11-01
中文翻译:
血清素通过干扰时钟来防止棕色脂肪细胞的分化。
显示5-羟色胺会干扰棕色脂肪细胞的分化。另外,时钟成分通过直接转录控制转化生长因子β途径的关键成分来抑制褐色脂肪形成。这项研究的目的是研究5-羟色胺是否通过影响时钟功能来消除褐色脂肪形成。