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Lipoic acid a multi-level molecular inhibitor of tumorigenesis.
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer ( IF 11.2 ) Pub Date : 2019-11-01 , DOI: 10.1016/j.bbcan.2019.188317
D Farhat 1 , H Lincet 2
Affiliation  

We discuss how lipoic acid (LA), a natural antioxidant, induces apoptosis and inhibits proliferation, EMT, metastasis and stemness of cancer cells. Furthermore, owing to its ability to reduce chemotherapy-induced side effects and chemoresistance, LA appears to be a promising compound for cancer treatment.

中文翻译:

硫辛酸是肿瘤发生的多水平分子抑制剂。

我们讨论了天然抗氧化剂硫辛酸(LA)如何诱导细胞凋亡并抑制癌细胞的增殖,EMT,转移和干性。此外,由于其具有降低化疗诱导的副作用和化学抗药性的能力,LA似乎是一种有前途的癌症治疗化合物。
更新日期:2019-11-01
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