Intolerance of uncertainty is a dispositional trait associated with a range of psychological disorders, but the influence of methodological factors on theses associations remains unknown. The first aim of this meta-analysis was to quantify the strengths of the association between IU and symptoms of generalised anxiety disorder, social anxiety disorder, panic disorder, agoraphobia, obsessive compulsive disorder, depression, and eating disorders. The second aim was to assess the influence of methodological factors on these relationships, including clinical (vs. non-clinical) status, age group, sex, IU measure, and symptom measure. We extracted 181 studies (N participants = 52,402) reporting 335 independent effect sizes (Pearson's r). Overall, there was a moderate association between IU and symptoms (r = 0.51, 95% CI = 0.50–0.52), although heterogeneity was high (I² = 83.50, p < .001). Some small but significant moderator effects emerged between and within disorders. Effect sizes were not impacted by sample size. The results indicate that IU has robust, moderate associations with a range of disorder symptoms, providing definitive evidence for the transdiagnostic nature of IU.

不确定性的不宽容是与一系列心理障碍相关的性格特征，但是方法论因素对这些联想的影响仍然未知。这项荟萃分析的首要目的是量化IU与广泛性焦虑症，社交焦虑症，恐慌症，恐旷症，强迫症，抑郁症和进食障碍的症状之间的关联强度。第二个目的是评估方法因素对这些关系的影响，包括临床（相对于非临床）状况，年龄组，性别，IU量度和症状量度。我们提取了181个研究（N个参与者= 52,402），报告了335个独立的效应量（Pearson's r）。总体而言， 尽管异质性很高（I ²  = 83.50，p  <.001），但IU与症状之间存在中等关联（r = 0.51，95％CI = 0.50–0.52 ）。在疾病之间和疾病内部出现了一些小的但重要的调节作用。效应量不受样本量的影响。结果表明，IU与一系列疾病症状具有稳固，适度的关联，为IU的转诊性质提供了明确的证据。