当前位置:
X-MOL 学术
›
J. Intern. Med.
›
论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Iron deficiency anaemia revisited.
Journal of Internal Medicine ( IF 11.1 ) Pub Date : 2019-10-30 , DOI: 10.1111/joim.13004 M D Cappellini 1 , K M Musallam 2 , A T Taher 3
Journal of Internal Medicine ( IF 11.1 ) Pub Date : 2019-10-30 , DOI: 10.1111/joim.13004 M D Cappellini 1 , K M Musallam 2 , A T Taher 3
Affiliation
Iron deficiency anaemia is a global health concern affecting children, women and the elderly, whilst also being a common comorbidity in multiple medical conditions. The aetiology is variable and attributed to several risk factors decreasing iron intake and absorption or increasing demand and loss, with multiple aetiologies often coexisting in an individual patient. Although presenting symptoms may be nonspecific, there is emerging evidence on the detrimental effects of iron deficiency anaemia on clinical outcomes across several medical conditions. Increased awareness about the consequences and prevalence of iron deficiency anaemia can aid early detection and management. Diagnosis can be easily made by measurement of haemoglobin and serum ferritin levels, whilst in chronic inflammatory conditions, diagnosis may be more challenging and necessitates consideration of higher serum ferritin thresholds and evaluation of transferrin saturation. Oral and intravenous formulations of iron supplementation are available, and several patient and disease-related factors need to be considered before management decisions are made. This review provides recent updates and guidance on the diagnosis and management of iron deficiency anaemia in multiple clinical settings.
中文翻译:
重度缺铁性贫血。
缺铁性贫血是一种影响儿童,妇女和老年人的全球性健康问题,同时也是多种医疗条件下的常见合并症。病因是可变的,并归因于降低铁摄入和吸收或增加需求和损失的几种风险因素,而个别患者通常并存多种病因。尽管表现的症状可能是非特异性的,但有证据表明,铁缺乏症贫血对多种医学状况的临床结果均具有不利影响。对缺铁性贫血的后果和流行的认识的提高可以帮助及早发现和管理。在慢性炎症条件下,通过测量血红蛋白和血清铁蛋白水平可以很容易地进行诊断,诊断可能更具挑战性,需要考虑更高的血清铁蛋白阈值和转铁蛋白饱和度评估。可以使用口服和静脉补铁的配方,在做出管理决定之前,需要考虑一些与患者和疾病相关的因素。这项审查提供了多种临床环境中铁缺乏性贫血的诊断和管理的最新更新和指导。
更新日期:2019-11-13
中文翻译:
重度缺铁性贫血。
缺铁性贫血是一种影响儿童,妇女和老年人的全球性健康问题,同时也是多种医疗条件下的常见合并症。病因是可变的,并归因于降低铁摄入和吸收或增加需求和损失的几种风险因素,而个别患者通常并存多种病因。尽管表现的症状可能是非特异性的,但有证据表明,铁缺乏症贫血对多种医学状况的临床结果均具有不利影响。对缺铁性贫血的后果和流行的认识的提高可以帮助及早发现和管理。在慢性炎症条件下,通过测量血红蛋白和血清铁蛋白水平可以很容易地进行诊断,诊断可能更具挑战性,需要考虑更高的血清铁蛋白阈值和转铁蛋白饱和度评估。可以使用口服和静脉补铁的配方,在做出管理决定之前,需要考虑一些与患者和疾病相关的因素。这项审查提供了多种临床环境中铁缺乏性贫血的诊断和管理的最新更新和指导。