BACKGROUND PTSD in youth may lead to long-lasting psychological implications, educational difficulties and increased healthcare costs. Psychological interventions have been shown to be effective in its management. The objective of this study was to assess the cost-effectiveness of a range of psychological interventions for children and young people with PTSD. METHODS A decision-analytic model was constructed to compare costs and quality-adjusted life years (QALYs) of 10 psychological interventions and no treatment for children and young people with PTSD, from the perspective of the National Health Service and personal social services in England. Effectiveness data were derived from a systematic review and network meta-analysis. Other model input parameters were based on published sources, supplemented by expert opinion. RESULTS Cognitive therapy for PTSD, a form of individual trauma-focused cognitive behavioural therapy (TF-CBT), appeared to be the most cost-effective intervention for children and young people with PTSD (with a probability of .78 amongst the 11 evaluated options at a cost-effectiveness threshold of £20,000/QALY), followed by narrative exposure (another form of individual TF-CBT), play therapy, and other forms of individual TF-CBT. After excluding cognitive therapy from the analysis, narrative exposure appeared to be the most cost-effective option with a .40 probability of being cost-effective amongst the remaining 10 options. EMDR, parent training and group TF-CBT occupied middle cost-effectiveness rankings. Family therapy and supportive counselling were less cost-effective than other active interventions. There was limited evidence for some interventions, in particular cognitive therapy for PTSD and parent training. CONCLUSIONS Individual forms of TF-CBT and, to a lesser degree, play therapy appear to be cost-effective in the treatment of children and young people with PTSD. Family therapy and supportive counselling are unlikely to be cost-effective relative to other interventions. There is a need for well-conducted studies that examine the long-term clinical and cost-effectiveness of a range of psychological treatments for children and young people with PTSD.

中文翻译：

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对患有创伤后应激障碍的儿童和年轻人进行心理干预的成本效益。

背景 青年人的 PTSD 可能会导致长期的心理影响、教育困难和医疗费用增加。心理干预已被证明对其管理有效。本研究的目的是评估一系列针对患有 PTSD 的儿童和青少年的心理干预措施的成本效益。方法 从英国国家卫生服务和个人社会服务的角度构建决策分析模型，以比较 10 种心理干预和未治疗 PTSD 儿童和青少年的成本和质量调整生命年 (QALY)。有效性数据来自系统评价和网络荟萃分析。其他模型输入参数基于已发表的来源，并辅以专家意见。结果 PTSD 的认知疗法是一种以个体创伤为中心的认知行为疗法 (TF-CBT)，似乎是对患有 PTSD 的儿童和年轻人最具成本效益的干预措施（在 11 个评估选项中的概率为 0.78以 20,000 英镑/QALY 的成本效益阈值），然后是叙事暴露（另一种形式的个人 TF-CBT）、游戏治疗和其他形式的个人 TF-CBT。从分析中排除认知疗法后，叙事暴露似乎是最具成本效益的选择，在其余 10 个选项中具有成本效益的概率为 0.40。EMDR、家长培训和团体 TF-CBT 占据中等成本效益排名。家庭治疗和支持性咨询的成本效益低于其他积极干预措施。某些干预措施的证据有限，尤其是针对 PTSD 的认知疗法和家长培训。结论 个体形式的 TF-CBT 以及在较小程度上的游戏疗法在治疗患有 PTSD 的儿童和年轻人中似乎具有成本效益。与其他干预措施相比，家庭治疗和支持性咨询不太可能具有成本效益。需要进行良好的研究，以检验针对患有 PTSD 的儿童和青少年的一系列心理治疗的长期临床和成本效益。与其他干预措施相比，家庭治疗和支持性咨询不太可能具有成本效益。需要进行良好的研究，以检验针对患有 PTSD 的儿童和青少年的一系列心理治疗的长期临床和成本效益。与其他干预措施相比，家庭治疗和支持性咨询不太可能具有成本效益。需要进行良好的研究，以检查一系列针对患有 PTSD 的儿童和年轻人的心理治疗的长期临床和成本效益。