This cross‐sectional study examined the burden of depression and quality of life (QoL) among mothers of children with autism spectrum disorder (ASD) attending six schools offering special educational services for children with ASD in urban Dhaka, Bangladesh. All consenting mothers were 18 years of age and older and met criteria for major depressive disorder (MDD) on the Structured Interview for DSM‐V‐TR Research Version‐non patient edition administered by trained raters. QoL was assessed by the EuroQol five‐dimensional standardized questionnaire. MDD was diagnosed in 45% of mothers and was proportionally higher among those who did not work outside the home, had no childcare support at home, expressed low level of satisfaction with the quality of providers when they had sought care for their children with ASD, and reported being recipient of negative attitudes from neighbors toward their children with ASD. QoL was negatively associated with MDD, mothers' illness, and low satisfaction with the health care providers for children with ASD, as well as experiencing a negative attitude by neighbors toward their children. QoL was positively associated with the reported family monthly income and improvement of the children with ASD on school attendance. The prevalence of MDD among mothers of children with ASD was high and associated with poor QoL. Integrating mental health services and supports for mothers in the ASD care of children is likely to address the high burden of depression they face, and improve their overall quality of life. Autism Res 2020, 13: 284–297. © 2019 International Society for Autism Research, Wiley Periodicals, Inc.

中文翻译：

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孟加拉国城市自闭症谱系障碍儿童母亲的主要抑郁症负担和生活质量。

这项横断面研究调查了自闭症谱系障碍（ASD）儿童的母亲在孟加拉国达卡市的六所学校提供的自闭症儿童特殊教育服务所面临的抑郁负担和生活质量（QoL）。所有同意的母亲均年满18岁，并符合由训练有素的评分者管理的DSM‐V‐TR研究版（非患者版）《结构化面试》中的重度抑郁症（MDD）标准。QoL由EuroQol五维标准化问卷进行了评估。在45％的母亲中诊断出MDD，在没有在家工作，在家中没有托儿服务的母亲中，比例较高。当他们为ASD的孩子寻求照料时，对提供者的质量表示不满意，并报告说邻居们接受了邻居对患有自闭症的孩子的负面态度。生活质量与MDD，母亲的疾病以及对ASD儿童的医疗保健服务提供者的满意度不高以及邻居对孩子的态度消极有关。生活质量与所报告的家庭月收入和ASD儿童入学率的改善呈正相关。患有自闭症儿童的母亲中MDD的患病率很高，并且与QoL差有关。将精神保健服务和对母亲的支持纳入ASD儿童照护中，可能会解决他们面临的沉重抑郁症负担，并改善他们的整体生活质量。对ASD儿童的医疗保健提供者的满意度低，以及邻居对他们的孩子持消极态度。生活质量与所报告的家庭月收入和ASD儿童入学率的改善呈正相关。患有自闭症儿童的母亲中MDD的患病率很高，并且与QoL差有关。将精神保健服务和对母亲的支持纳入ASD儿童照护中，可能会解决他们面临的沉重抑郁症负担，并改善他们的整体生活质量。对ASD儿童的医疗保健提供者的满意度低，以及邻居对他们的孩子持消极态度。生活质量与所报告的家庭月收入和ASD儿童入学率的改善呈正相关。患有自闭症儿童的母亲中MDD的患病率很高，并且与QoL差有关。将精神保健服务和对母亲的支持纳入ASD儿童照护中，可能会解决他们面临的沉重抑郁症负担，并改善他们的整体生活质量。生活质量与所报告的家庭月收入和ASD儿童入学率的改善呈正相关。患有自闭症儿童的母亲中MDD的患病率很高，并且与QoL差有关。将精神保健服务和对母亲的支持纳入ASD儿童照护中，可能会解决他们面临的沉重抑郁症负担，并改善他们的整体生活质量。生活质量与所报告的家庭月收入和ASD儿童入学率的改善呈正相关。患有自闭症儿童的母亲中MDD的患病率很高，并且与QoL差有关。将精神保健服务和对母亲的支持纳入ASD儿童照护中，可能会解决他们面临的沉重抑郁症负担，并改善他们的整体生活质量。Autism Res 2020，13：284-297。©2019国际自闭症研究会，Wiley Periodicals，Inc.