This study explored Candida antarctica lipase B (CALB) non-covalently immobilized on multiwalled carbon nanotubes for the preparation of metal-free (co)polymers of ε-caprolactone (CL) and trimethylene carbonate (TMC). The novel catalytic/initiating system based on nanobiocatalyst and 1,5-pentanediol allows for the control over the molar mass (M_n) of the obtained homopolymers and copolymers. M_n of polymers, ranged from 5.0 to 50 kg/mol, was controlled by monomer to initiator ratio. Their microstructure was investigated by ¹³C NMR, while thermal properties by DSC. In addition, the recycling studies indicate that nanobiocatalyst can be used multiple times without loss in its activity. The application of non-toxic catalyst for the polymers preparation is of high importance for their industrial and biomedical applications. Therefore, our novel and versatile approach for the controlled synthesis of the CL and TMC (co)polymers for which the nanobiocatalyst can be used several times, enable to address the demand for the “metal-free (co)polymers”.

这项研究探索了非共价固定在多壁碳纳米管上的南极假丝酵母脂肪酶B（CALB），用于制备ε-己内酯（CL）和碳酸三亚甲基酯（TMC）的无金属（共）聚合物。基于纳米生物催化剂和1，5-戊二醇的新型催化/引发体系允许控制所获得的均聚物和共聚物的摩尔质量（M _n）。中号_Ñ聚合物，范围为5.0至50千克/摩尔，通过单体与引发剂的比例来控制。他们的微观结构由^13个进行了研究13 C NMR，而热性质由DSC确定。此外，回收研究表明，纳米生物催化剂可以多次使用而不会损失其活性。无毒催化剂在聚合物制备中的应用对其工业和生物医学应用具有重要意义。因此，我们新颖且用途广泛的可控制合成CL和TMC（共）聚合物的方法（纳米生物催化剂可多次使用）可满足对“无金属（共）聚合物”的需求。