AIM To test if exposure to unemployment in young adulthood is associated with an increased risk of later alcohol-related morbidity. DESIGN A nationwide register-linked longitudinal population-based study. SETTING Sweden. PARTICIPANTS A total of 16 490 individuals born between 1967 and 1978, who had participated in the Labour Force Survey between the ages of 16-24 during the years of 1990-1995. MEASUREMENT Information on the outcome of alcohol-related morbidity was obtained from the National Hospital Discharge Register. The Swedish index of alcohol-related inpatient care was used to define the outcome. Information on sex, age, and country of birth, as well as parents' level of education, socioeconomic status, and alcohol-related health problems, were also obtained. Average follow-up time was 22 years. Cox regression analysis was used to obtain Hazard ratios (HR) with 95% confidence intervals (CI). FINDINGS Compared with full-time students, individuals who experienced short- and long-term unemployment spells at a young age were at an increased risk of later alcohol-related morbidity; <3 months (HR: 2.04; 95% CI 1.35 to 3.09), 3 to 6 months (2.20; 1.29 to 3.75) and >6 months (1.99; 1.06 to 3.71) of unemployment, after adjusting for several important individual and family level covariates. CONCLUSION In Sweden, a nationwide registered based study with a 22-year follow-up suggests that being unemployed in young adulthood is associated with an increased risk of alcohol-related morbidity later in life.

中文翻译：

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青年失业对酒精相关发病率的长期影响

目的 测试青年时期失业是否与后期酒精相关发病率的增加有关。设计 一项全国范围的登记相关纵向人群研究。设置瑞典。参与者 共有 16 490 名出生于 1967 年至 1978 年的人参加了 1990 年至 1995 年期间 16 至 24 岁之间的劳动力调查。测量从国家医院出院登记处获得有关酒精相关发病率结果的信息。瑞典酒精相关住院护理指数用于定义结果。还获得了关于性别、年龄和出生国家以及父母的教育水平、社会经济地位和与酒精有关的健康问题的信息。平均随访时间为 22 年。Cox 回归分析用于获得具有 95% 置信区间 (CI) 的风险比 (HR)。研究结果 与全日制学生相比，在年轻时经历过短期和长期失业的人后来患酒精相关疾病的风险更高；<3 个月（HR：2.04；95% CI 1.35 至 3.09）、3 至 6 个月（2.20；1.29 至 3.75）和 ​​>6 个月（1.99；1.06 至 3.71）的失业，在调整几个重要的个人和家庭水平后协变量。结论 在瑞典，一项全国性注册研究和 22 年随访表明，年轻时失业与晚年与酒精相关的发病风险增加有关。在年轻时经历过短期和长期失业的人，后来患酒精相关疾病的风险增加；<3 个月（HR：2.04；95% CI 1.35 至 3.09）、3 至 6 个月（2.20；1.29 至 3.75）和 ​​>6 个月（1.99；1.06 至 3.71）的失业，在调整几个重要的个人和家庭水平后协变量。结论 在瑞典，一项为期 22 年的全国性注册研究表明，年轻时失业与晚年与酒精相关的发病风险增加有关。在年轻时经历过短期和长期失业的人，后来患酒精相关疾病的风险增加；<3 个月（HR：2.04；95% CI 1.35 至 3.09）、3 至 6 个月（2.20；1.29 至 3.75）和 ​​>6 个月（1.99；1.06 至 3.71）的失业，在调整几个重要的个人和家庭水平后协变量。结论 在瑞典，一项为期 22 年的全国性注册研究表明，年轻时失业与晚年与酒精相关的发病风险增加有关。在调整了几个重要的个人和家庭水平协变量之后。结论 在瑞典，一项为期 22 年的全国性注册研究表明，年轻时失业与晚年与酒精相关的发病风险增加有关。在调整了几个重要的个人和家庭水平协变量之后。结论 在瑞典，一项全国性注册研究和 22 年随访表明，年轻时失业与晚年与酒精相关的发病风险增加有关。