The genome is folded nonrandomly inside the cell nucleus. How this contributes to gene regulation is an important subject of investigation. A new study by Despang et al. shows how the spatial segregation of genes and regulatory regions can influence developmental expression in subtle, but critical ways.

中文翻译：

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基因调控知道其边界。

基因组在细胞核内无规折叠。这如何促进基因调控是重要的研究课题。Despang等人的一项新研究。展示了基因和调控区的空间分离如何以微妙但关键的方式影响发育表达。