The majority of patients with stroke survive the acute episode and live with enduring disability. Effective therapies to support recovery of motor function after stroke are yet to be developed. Key to this development is the identification of neurophysiologic signals that mark recovery and are suitable and susceptible to interventional therapies. Movement preparatory low‐frequency oscillations (LFOs) play a key role in cortical control of movement. Recent animal data point to a mechanistic role of motor cortical LFOs in stroke motor deficits and demonstrate neuromodulation intervention with therapeutic benefit. Their relevance in human stroke pathophysiology is unknown.

中文翻译：

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低频脑震荡跟踪人类中风的运动恢复

大多数中风患者在急性发作后幸存下来，并伴随着持久的残疾。支持中风后运动功能恢复的有效疗法尚待开发。这一发展的关键是识别神经生理信号，这些信号标志着恢复并且适合和易受介入疗法的影响。运动准备低频振荡 (LFO) 在皮层运动控制中起着关键作用。最近的动物数据表明运动皮质 LFO 在中风运动缺陷中的机械作用，并证明神经调节干预具有治疗益处。它们在人类中风病理生理学中的相关性尚不清楚。