Prediction of Alzheimer's disease diagnosis within 14 years through Aβ misfolding in blood plasma compared to APOE4 status, and other risk factors,Alzheimer's & Dementia

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Prediction of Alzheimer's disease diagnosis within 14 years through Aβ misfolding in blood plasma compared to APOE4 status, and other risk factors
Alzheimer's & Dementia ( IF 14.0 ) Pub Date : 2020-01-06 , DOI: 10.1016/j.jalz.2019.08.189
Hannah Stocker _{1,

2,

3} , Andreas Nabers ₄ , Laura Perna _{2,

5} , Tobias Möllers _{1,

2,

3} , Dan Rujescu ₆ , Annette Hartmann ₆ , Bernd Holleczek ₇ , Ben Schöttker _{1,

2} , Klaus Gerwert ₄ , Hermann Brenner _{1,

2}

Affiliation

Alzheimer's disease (AD) has a long prodromal stage and identifying high‐risk individuals is critical. We aimed to investigate the ability of Aβ misfolding in blood plasma, APOE4 status, and dementia risk factors to predict diagnosis of AD.

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