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Systemic serotonin inhibits brown adipose tissue sympathetic nerve activity via a GABA input to the dorsomedial hypothalamus, not via 5HT1A receptor activation in raphe pallidus.
Acta Physiologica ( IF 6.3 ) Pub Date : 2019-11-01 , DOI: 10.1111/apha.13401
Clarissa M D Mota 1, 2 , Luiz G S Branco 2, 3 , Shaun F Morrison 1 , Christopher J Madden 1
Affiliation  

Serotonin (5‐hydroxytryptamine, 5‐HT), an important neurotransmitter and hormone, modulates many physiological functions including body temperature. We investigated neural mechanisms involved in the inhibition of brown adipose tissue (BAT) sympathetic nerve activity (SNA) and BAT thermogenesis evoked by 5‐HT.

中文翻译:

全身性5-羟色胺通过输入到丘脑下丘脑的GABA而不是通过麻痹中的5HT1A受体激活来抑制棕色脂肪组织的交感神经活动。

血清素(5-羟色胺,5-HT)是一种重要的神经递质和激素,可调节包括体温在内的许多生理功能。我们研究了抑制5-HT引起的棕色脂肪组织(BAT)交感神经活性(SNA)和BAT生热的神经机制。
更新日期:2019-11-01
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