A total of 24 non-antibiotic compounds were tested for their antimicrobial activity against Escherichia coli, Klebsiella pneumoniae (ATCC) and an MDR strain of Acinetobacter baumannii using an agar well diffusion assay. To study additive effects, 100 µl of each antibiotic and 50 µl of each non-antibiotic were used. Cloprostenol was the only non-antibiotic that showed antibacterial activity against all bacterial strains. Cloprostenol had an additive antimicrobial effect with the tested antibiotics against the MDR A. baumannii strain.

中文翻译：

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鉴定氯前列腺素的新型体外抗菌作用并评估其他非抗生素对多重耐药鲍曼不动杆菌的抵抗力。

使用琼脂井扩散测定法测试了总共24种非抗生素化合物对大肠杆菌，肺炎克雷伯菌（ATCC）和鲍曼不动杆菌的MDR菌株的抗菌活性。为了研究累加效应，分别使用了100 µl的每种抗生素和50 µl的每种非抗生素。氯前列醇是唯一对所有细菌菌株均具有抗菌活性的非抗生素。氯前列醇对被测试的抗生素具有抗MDR鲍曼不动杆菌菌株的附加抗菌作用。