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Virus Impact on Lipids and Membranes.
Annual Review of Virology ( IF 11.3 ) Pub Date : 2019-09-29 , DOI: 10.1146/annurev-virology-092818-015748
Ellen Ketter 1 , Glenn Randall 1
Affiliation  

Viruses manipulate cellular lipids and membranes at each stage of their life cycle. This includes lipid-receptor interactions, the fusion of viral envelopes with cellular membranes during endocytosis, the reorganization of cellular membranes to form replication compartments, and the envelopment and egress of virions. In addition to the physical interactions with cellular membranes, viruses have evolved to manipulate lipid signaling and metabolism to benefit their replication. This review summarizes the strategies that viruses use to manipulate lipids and membranes at each stage in the viral life cycle.

中文翻译:

病毒对脂质和膜的影响。

病毒在生命周期的每个阶段都操纵细胞脂质和细胞膜。这包括脂质-受体相互作用,内吞过程中病毒被膜与细胞膜的融合,细胞膜的重组以形成复制区室以及病毒体的包封和流出。除了与细胞膜的物理相互作用外,病毒还进化为可操纵脂质信号传导和代谢,从而有利于其复制。这篇综述总结了病毒在病毒生命周期的每个阶段用来操纵脂质和膜的策略。
更新日期:2020-04-21
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