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Cognitive processes predicting advanced theory of mind in the broader autism phenotype.
Autism Research ( IF 4.7 ) Pub Date : 2019-09-30 , DOI: 10.1002/aur.2209
Cherie C Green 1 , Natasha J Brown 2, 3, 4, 5 , Valerie M Z Yap 6 , Ingrid E Scheffer 1, 4, 7 , Sarah J Wilson 6, 7
Affiliation  

Little is known about executive functions (EFs) associated with advanced theory of mind (ToM) abilities. We aimed to determine if advanced ToM abilities were reduced in individuals with subclinical traits of autism spectrum disorder (ASD), known as the “Broader Autism Phenotype” (BAP), and identify the EFs that predicted unimpaired performance on an advanced ToM task, the faux pas test. We assessed 29 participants (13 males) with the BAP who were relatives of children with ASD. Thirteen participants showed reduced ability to understand a faux pas. A discriminant function analysis correctly classified 79% of cases as impaired or unimpaired, with high sensitivity (80%) and specificity (77%), which was best predicted by language‐mediated EFs, including verbal generativity, working memory, cognitive inhibition, and flexibility. Autism Res 2020, 13: 921‐934. © 2019 International Society for Autism Research, Wiley Periodicals, Inc.

中文翻译:

认知过程在更广泛的自闭症表型中预测先进的心理理论。

对于与高级心智理论(ToM)能力相关的执行功能(EF)知之甚少。我们旨在确定具有自闭症谱系障碍(ASD)亚临床特征(称为“更广泛的自闭症表型”(BAP))的个人的高级ToM能力是否降低,并确定可预测高级ToM任务表现不受影响的EF。假pas测试。我们评估了29名BAP参与者(13名男性),他们是ASD儿童的亲戚。十三名参与者表现出的虚假理解能力下降。判别功能分析正确地将79%的病例分类为受损或未受损,具有高敏感性(80%)和特异性(77%),这是通过语言介导的EF最好的预测,包括言语生成能力,工作记忆,认知抑制和灵活性。自闭症水库2020年,13:921-934。©2019国际自闭症研究会,Wiley Periodicals,Inc.
更新日期:2019-09-30
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