PURPOSE To determine whether differences in sclerotomy size during intrascleral intraocular lens (IOL) fixation influence IOL tilt and visual acuity after surgery. SETTING University of Fukui Hospital and Japanese Red Cross Fukui Hospital, Japan. DESIGN Retrospective case series. METHODS The study reviewed the records of patients who had intrascleral IOL fixation with transconjunctival 25-gauge pars plana vitrectomy and a follow-up longer than 6 months. The preoperative and postoperative visual outcomes, degree of IOL tilt, and intraoperative and postoperative complications were statistically compared between the sclerotomy groups. RESULTS The study included 65 eyes (60 patients). Postoperatively, the maximum degree of IOL tilt was significantly smaller in the 24-gauge sclerotomy group than in the 30-gauge sclerotomy group (P = .003). The degree of IOL tilt was significantly correlated with the amount of postoperative IOL astigmatism (total astigmatism - corneal astigmatism) (P = .0001, R2 = 0.23). There were no statistically significant differences in the preoperative or postoperative corrected distance visual acuity (CDVA) or the complication rate between the sclerotomy groups. CONCLUSION A smaller sclerotomy for intrascleral IOL fixation was associated with greater IOL tilt and IOL astigmatism after surgery; however, this did not clinically or significantly affect the postoperative CDVA.

中文翻译：

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巩膜切开术大小对巩膜内人工晶状体固定后人工晶状体倾斜的影响。

目的确定巩膜内人工晶状体（IOL）固定期间巩膜切开术大小的差异是否影响手术后IOL倾斜和视敏度。地点日本福井大学医院和日本红十字会福井医院。设计回顾案系列。方法该研究回顾了结膜内25孔标准尺玻璃体玻璃体切除术并进行了超过6个月随访的巩膜内人工晶状体固定术的患者的记录。硬膜切开术组之间比较了术前和术后的视觉结果，IOL倾斜度以及术中和术后并发症。结果该研究包括65只眼（60例患者）。术后，24号硬化症患者的最大IOL倾斜度明显小于30号硬化症患者（P = .003）。IOL倾斜度与术后IOL散光（总散光-角膜散光）的数量显着相关（P = .0001，R2 = 0.23）。硬化切开术组之间的术前或术后矫正远视力（CDVA）或并发症发生率无统计学差异。结论巩膜内人工晶状体固定术较小的巩膜切开术与手术后较大的人工晶状体倾斜度和人工晶状体散光有关。但是，这并没有在临床上或显着影响术后CDVA。硬化切开术组之间的术前或术后矫正远视力（CDVA）或并发症发生率无统计学差异。结论巩膜内人工晶状体固定术的硬化剂量较小与手术后较大的人工晶状体倾斜度和人工晶状体散光有关。但是，这并没有在临床上或显着影响术后CDVA。硬化切开术组之间的术前或术后矫正远视力（CDVA）或并发症发生率无统计学差异。结论巩膜内人工晶状体固定术的硬化剂量较小与手术后较大的人工晶状体倾斜度和人工晶状体散光有关。但是，这并没有在临床上或显着影响术后CDVA。