PURPOSE To evaluate the long-term refractive and visual, anterior chamber depth, and axial length (AL) changes and complications after rigid iris-fixated phakic intraocular lens (pIOL) implantation to treat myopia or astigmatism. SETTING University Eye Clinic Maastricht, Maastricht UMC+, the Netherlands. DESIGN Prospective case series. METHODS The study evaluated patients who had implantation of an Artisan myopic or toric iris-fixated pIOL as of January 1998. Changes were measured annually and reported after 1, 5, and 10 years postoperatively. RESULTS The study comprised 460 eyes (250 patients; mean age 41.1 years ± 10.7 [SD]). Over 10 years, the mean myopization was -0.79 diopters (D) (P < .001), with 52% of eyes within ±1.0 D of target. The mean increase in the logarithm of the minimum angle of resolution (logMAR) corrected distance visual acuity (CDVA) over 10 years was 0.05 (P < .001); 95% of eyes had a CDVA of 20/40 or more and 7% lost 2 or more lines of CDVA. The mean logMAR uncorrected visual acuity (UDVA) increased by 0.14 over 10 years (P < .001); 96% had a UDVA 20/40 or better. The AL increased by 1.14 mm over 10 years (P = .009). Ten percent of pIOLs were explanted because of cataract formation after a mean of 97.9 ± 34.9 months. A higher preoperative age (hazard ratio [HR], 1.08; P < .001) and longer AL (HR, 1.34; P < .001) were risk factors for shorter survival because of cataract formation. CONCLUSION Ten years after rigid iris-fixated pIOL implantation, the CDVA and UDVA decreased significantly as a result of significant myopization caused by an increased AL unrelated to the pIOL.

中文翻译：

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近视和复曲面有晶状体人工晶状体植入后视觉效果和眼形的长期变化：五年和十年的结果。

目的评估硬性虹膜固定有晶状体人工晶状体（pIOL）植入治疗近视或散光后的长期屈光和视觉，前房深度和轴长（AL）的变化及并发症。地点荷兰马斯特里赫特UMC +的马斯特里赫特大学眼科诊所。设计预期案例系列。方法该研究评估了自1998年1月起植入Artisan近视眼或复曲面虹膜固定pIOL的患者。每年进行测量，并在术后1年，5年和10年报告其变化。结果该研究包括460只眼睛（250名患者；平均年龄41.1岁±10.7 [SD]）。在10年中，平均近视度数为-0.79屈光度（D）（P <.001），其中52％的眼睛在目标的±1.0 D之内。最小分辨角（logMAR）校正的距离视力（CDVA）的10年对数平均增加0.05（P <.001）；95％的眼睛的CDVA为20/40或更多，而7％的眼睛失去了2条或更多的CDVA。10年来，平均logMAR未矫正视力（UDVA）增加了0.14（P <.001）；96％的UDVA为20/40或更高。10年内AL增加1.14 mm（P = .009）。在平均97.9±34.9个月后，由于白内障的形成，有10％的pIOL被移出。较高的术前年龄（危险比[HR]为1.08； P <.001）和较长的AL（HR为1.34； P <.001）是由于白内障形成而导致生存期缩短的危险因素。结论刚性虹膜固定的pIOL植入十年后，