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REPLY: Portal Pressure in Non‐Cirrhotic Portal Hypertension: To Measure or Not to Measure
Hepatology ( IF 13.5 ) Pub Date : 2020-01-01 , DOI: 10.1002/hep.30955 Ben L Da 1 , Christopher Koh 2 , Theo Heller 2
Hepatology ( IF 13.5 ) Pub Date : 2020-01-01 , DOI: 10.1002/hep.30955 Ben L Da 1 , Christopher Koh 2 , Theo Heller 2
Affiliation
We appreciate the interest in our work and the commentary provided by Professor Kumar and colleagues. To clarify, we do believe that hepatic venous pressure gradient (HVPG) measurement is a viable clinical tool that can be used in addition to liver biopsy in distinguishing non-cirrhotic portal hypertension (NCPH) versus cirrhosis. However, this is rarely necessary unless tissue sample obtained during the biopsy is insufficient. Performance of HVPG measurements, compared to percutaneous liver biopsy, subject patients to prolonged procedure times, requires additional allocation of medical resources, all while resulting in smaller and narrower cores that make histologic interpretation less reliable.(1) The latter being the most crucial liability as the tissue itself is the gold standard in differentiating NCPH from cirrhosis.
中文翻译:
回复:非肝硬化门静脉高压症的门静脉压力:测量或不测量
我们感谢库马尔教授及其同事对我们的工作和评论的兴趣。澄清一下,我们确实相信肝静脉压力梯度 (HVPG) 测量是一种可行的临床工具,除了肝活检外,还可用于区分非肝硬化门脉高压 (NCPH) 与肝硬化。然而,除非在活组织检查期间获得的组织样本不足,否则这很少是必要的。与经皮肝活检相比,HVPG 测量的性能使患者的手术时间延长,需要额外分配医疗资源,同时导致越来越小的核心,使组织学解释不太可靠。 (1) 后者是最重要的责任因为组织本身是区分 NCPH 与肝硬化的金标准。
更新日期:2020-01-01
中文翻译:
回复:非肝硬化门静脉高压症的门静脉压力:测量或不测量
我们感谢库马尔教授及其同事对我们的工作和评论的兴趣。澄清一下,我们确实相信肝静脉压力梯度 (HVPG) 测量是一种可行的临床工具,除了肝活检外,还可用于区分非肝硬化门脉高压 (NCPH) 与肝硬化。然而,除非在活组织检查期间获得的组织样本不足,否则这很少是必要的。与经皮肝活检相比,HVPG 测量的性能使患者的手术时间延长,需要额外分配医疗资源,同时导致越来越小的核心,使组织学解释不太可靠。 (1) 后者是最重要的责任因为组织本身是区分 NCPH 与肝硬化的金标准。