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Recent Advances in Enabling Technologies in 3D Printing for Precision Medicine.
Advanced Materials ( IF 29.4 ) Pub Date : 2019-09-12 , DOI: 10.1002/adma.201902516
Margaret E Prendergast 1 , Jason A Burdick 1
Affiliation  

Advances in areas such as data analytics, genomics, and imaging have revealed individual patient complexities and exposed the inherent limitations of generic therapies for patient treatment. These observations have also fueled the development of precision medicine approaches, where therapies are tailored for the individual rather than the broad patient population. 3D printing is a field that intersects with precision medicine through the design of precision implants with patient-directed shapes, structures, and materials or for the development of patient-specific in vitro models that can be used for screening precision therapeutics. Toward their success, advances in 3D printing and biofabrication technologies are needed with enhanced resolution, complexity, reproducibility, and speed and that encompass a broad range of cells and materials. The overall goal of this progress report is to highlight recent advances in 3D printing technologies that are helping to enable advances important in precision medicine.

中文翻译:

精密医学3D打印支持技术的最新进展。

数据分析,基因组学和成像等领域的进步揭示了个体患者的复杂性,并暴露了用于患者治疗的通用疗法的固有局限性。这些观察结果也推动了精密医学方法的发展,在这种方法中,针对个人而不是广大患者群体量身定制治疗方法。3D打印是通过设计具有患者导向的形状,结构和材料的精密植入物或开发可用于筛选精密治疗剂的特定于患者的体外模型来与精密医学相交的领域。为了获得成功,需要在3D打印和生物制造技术方面取得进步,以提高分辨率,复杂性,再现性和速度,并涵盖广泛的单元和材料。
更新日期:2020-04-01
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