A novel approach for the visible-light-initiated synthesis of 2-amino-4H-pyran-3,5-dicarbonitrile derivatives via a one-pot, three-component reaction of aldehydes or isatins, malononitrile, and α-cyano ketones has been developed. The reaction was carried out at room temperature in ethanol/water to give the corresponding products with a wide range of functional groups in high yields. This process did not require any additives or chromatographic separation and could be applied for gram-scale synthesis.

中文翻译：

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可见光引发的一锅，三组分2-氨基-4H-吡喃-3,5-二甲腈衍生物的合成。

通过醛或靛红，丙二腈和α-氰基酮的一锅三组分反应，可见光引发的合成2-氨基-4H-吡喃-3,5-二碳腈衍生物的新方法已经得到了应用。发达。该反应在室温下在乙醇/水中进行，以高收率得到具有广泛官能团的相应产物。该方法不需要任何添加剂或色谱分离，可用于克级合成。