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In vivo T cell CRISPR screens reveal immunotherapeutic targets.
Nature Reviews Cancer ( IF 78.5 ) Pub Date : 2019-11-01 , DOI: 10.1038/s41568-019-0207-8
Conor A Bradley 1
Affiliation  

In a study published in Cell, Dong et al. employ a genome-scale CRISPR screening approach to identify both known and previously uncharacterized regulators of CD8+ T cell activity, highlighting the utility of this approach for immunotherapeutic target dis…

中文翻译:

体内 T 细胞 CRISPR 筛选揭示了免疫治疗靶点。

在 Cell 上发表的一项研究中,Dong 等人。采用基因组规模的 CRISPR 筛选方法来识别已知和以前未表征的 CD8+ T 细胞活性调节因子,突出了这种方法在免疫治疗靶点分解中的实用性……
更新日期:2019-09-07
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