A catalytic system has been developed for the direct alkylation of α-C-H bonds of aniline derivatives with strained C-C σ-bonds. This method operates through a photoredox mechanism in which oxidative formation of aminoalkyl radical intermediates enables addition to a bicyclobutane derivative, giving rise to α-cyclobutyl N-alkylaniline products. This mild system proceeds through a redox- and proton-neutral mechanism and is operational for a range of substituted arylamine derivatives.

中文翻译：

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苯胺衍生物的自由基α-C-H环丁基化

已经开发了一种催化系统，用于直接烷基化苯胺衍生物的 α-CH 键，并具有应变的 CC σ 键。该方法通过光氧化还原机制进行操作，其中氨基烷基自由基中间体的氧化形成能够添加到双环丁烷衍生物中，从而产生 α-环丁基 N-烷基苯胺产物。这种温和的系统通过氧化还原和质子中性机制进行，可用于一系列取代的芳胺衍生物。