At the host-pathogen interface, the protein composition of the plasma membrane (PM) has important implications for how a plant cell perceives and responds to invading microbial pathogens. A plant's ability to modulate its PM composition is critical for regulating the strength, duration, and integration of immune responses. One mechanism by which plant cells reprogram their cell surface is vesicular trafficking, including secretion and endocytosis. These trafficking processes add or remove cargo proteins (such as pattern-recognition receptors, transporters, and other proteins with immune functions) to or from the PM via small, membrane-bound vesicles. Clathrin-coated vesicles (CCVs) that form at the PM and trans-Golgi network/early endosomes have emerged as the prominent vesicle type in the regulation of plant immune responses. In this review, we discuss the roles of the CCV core, adaptors, and accessory components in plant defense signaling and immunity against various microbial pathogens.

中文翻译：

---

永远不要独自行走：植物免疫中的网格蛋白涂层囊泡（CCV）组件。

在宿主-病原体界面，质膜（PM）的蛋白质组成对植物细胞如何感知和响应入侵的微生物病原体具有重要意义。植物调节其PM组成的能力对于调节免疫应答的强度，持续时间和整合至关重要。植物细胞对其细胞表面重新编程的一种机制是水泡运输，包括分泌和胞吞作用。这些运输过程通过膜结合的小囊泡向PM中添加或去除PM中的货物蛋白（例如模式识别受体，转运蛋白和其他具有免疫功能的蛋白）。在PM和反高尔基网络/早期内体形成的网格蛋白涂层囊泡（CCV）已成为调节植物免疫反应的主要囊泡类型。在这篇评论中，