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Inhibitory effects of pu-erh tea on alpha glucosidase and alpha amylase: a systemic review.
Nutrition & Diabetes ( IF 6.1 ) Pub Date : 2019-08-27 , DOI: 10.1038/s41387-019-0092-y
Chiung-Ying Yang , Yea-Yin Yen , Kuang-Chen Hung , Shang-Wei Hsu , Shou-Jen Lan , Hsin-Cheng Lin

OBJECTIVE Pu-erh tea was presumed to have anti-hyperglycemic effects via inhibition on alpha-amylase and alpha-glucosidase. However, no integerated literatures were published to substantiate such presumption. METHODS Current study adopted systemic review method to validate inhibitory effects on alpha amylase and alpha-glucosidase. Five English databases (PubMed, EBSCO, SCOPUS, Cochrane Library, Web of Science) and three Chinese ones (Airti Library, CNKI Library, and Google Scholar) were searched up to 22 March 2018 for eligible literatures, using keywords of Pu-erh, Pu'er, alpha-amylase or alpha-glucosidase. RESULTS Six studies exploring inhibitory effects on alpha-glucosidase and seven on alpha-amylase were included for systemic review. Though results showed pu-erh tea has significant inhibitory effects on alpha-amylase and alpha-glucosidase, high heterogeneity was detected among studies included. CONCLUSIONS High heterogeneity may be due to complex alterations of chemicals under different degrees of fermentation. More future studies are required to further identify principal bioactive component(s) at work.

中文翻译:

普-茶对α-葡萄糖苷酶和α-淀粉酶的抑制作用:系统评价。

目的普Pu茶被认为具有抑制α-淀粉酶和α-葡萄糖苷酶的降血糖作用。但是,没有公开的文献来证实这种推论。方法本研究采用系统评价方法,以验证对α淀粉酶和α-葡萄糖苷酶的抑制作用。截至2018年3月22日,使用Pu-erh关键字搜索了五个英文数据库(PubMed,EBSCO,SCOPUS,Cochrane图书馆,Web of Science)和三个中文数据库(Airti图书馆,CNKI图书馆和Google Scholar)以查找符合条件的文献。普',α-淀粉酶或α-葡萄糖苷酶。结果包括六项研究对α-葡萄糖苷酶抑制作用的研究和七项对α-淀粉酶抑制作用的研究进行系统评价。尽管结果表明普-茶对α-淀粉酶和α-葡萄糖苷酶具有显着的抑制作用,但在包括的研究中发现了高度异质性。结论高异质性可能是由于不同发酵程度下化学物质的复杂变化所致。需要进一步的研究来进一步确定工作中的主要生物活性成分。
更新日期:2019-08-27
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