Cardiovascular disease is one of the leading causes of mortality and morbidity worldwide. Atherosclerosis imaging has traditionally focused on detection of obstructive luminal stenoses or measurements of plaque burden. However, with advances in imaging technology it has now become possible to noninvasively interrogate plaque composition and disease activity, thereby differentiating stable from unstable patterns of disease and potentially improving risk stratification. This manuscript reviews multimodality imaging in this field, focusing on carotid and coronary atherosclerosis and how these novel techniques have the potential to complement current imaging assessments and improve clinical decision making.

中文翻译：

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无创成像评估动脉粥样硬化斑块成分和疾病活动性冠状动脉和颈动脉应用

心血管疾病是全世界死亡和发病的主要原因之一。动脉粥样硬化成像传统上侧重于检测阻塞性管腔狭窄或测量斑块负荷。然而，随着成像技术的进步，现在已经可以无创地询问斑块成分和疾病活动性，从而区分稳定和不稳定的疾病模式，并有可能改善风险分层。本手稿回顾了该领域的多模态成像，重点关注颈动脉和冠状动脉粥样硬化，以及这些新技术如何有可能补充当前的成像评估并改善临床决策。