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T cells pass on the baton during checkpoint inhibition.
Nature Reviews Cancer ( IF 78.5 ) Pub Date : 2019-10-01 , DOI: 10.1038/s41568-019-0194-9 Ulrike Harjes 1
Nature Reviews Cancer ( IF 78.5 ) Pub Date : 2019-10-01 , DOI: 10.1038/s41568-019-0194-9 Ulrike Harjes 1
Affiliation
Yost, Satpathy et al. show that the T cell response to immune checkpoint blockade consists of a repertoire of novel T cell clones, which are distinct from pre-existing exhausted T cell clones, and were not detected in the tumour before treatment.
中文翻译:
T 细胞在检查点抑制期间传递接力棒。
Yost, Satpathy 等人。表明 T 细胞对免疫检查点阻断的反应由一系列新的 T 细胞克隆组成,这些克隆不同于预先存在的耗尽的 T 细胞克隆,并且在治疗前在肿瘤中未检测到。
更新日期:2019-08-15
中文翻译:
T 细胞在检查点抑制期间传递接力棒。
Yost, Satpathy 等人。表明 T 细胞对免疫检查点阻断的反应由一系列新的 T 细胞克隆组成,这些克隆不同于预先存在的耗尽的 T 细胞克隆,并且在治疗前在肿瘤中未检测到。