Increased extracellular matrix stiffness has long been associated with malignant transformation in breast cancer. Now, Stowers et al. have shown that matrix stiffness induces a tumorigenic phenotype by affecting the epigenetic landscape of a cell.

中文翻译：

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面对一个残酷的事实。

长期以来，细胞外基质硬度的增加与乳腺癌的恶性转化有关。现在，斯托尔斯等人。已经表明，基质刚度通过影响细胞的表观遗传景观来诱导致瘤表型。