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The dietary combination of essential oils and organic acids reduces Salmonella enteritidis in challenged chicks.
Poultry Science ( IF 4.4 ) Pub Date : 2019-12-01 , DOI: 10.3382/ps/pez457
S Zhang 1, 2 , Y R Shen 1, 2 , S Wu 1, 2 , Y Q Xiao 1, 2 , Q He 3 , S R Shi 1, 2, 4
Affiliation  

This study was conducted to determine the effects of essential oils and organic acids (EOA) on Salmonella Enteritidis (S. Enteritidis) challenged chickens. One-day-old specific pathogen-free (SPF) chicks (250) were randomly assigned to 5 groups, with 50 birds in each group. The treatment groups were as follows: 1) basal diet, negative control group (NC); 2) basal diet + S. Enteritidis, positive control group (PC); 3) PC + 4,000 g/t of enrofloxacin (5%), antibiotic group (ENR); 4) PC + 800 g/t of EOA1, thymol-benzoic acid group (TBA); and 5) PC + 800 g/t of EOA2, cinnamylaldehyde-caproic acid group (CCA). At 7 D of age, each bird, except those in NC, was orally gavaged with 0.4 mL of a suspension of 4.4 × 109 cfu S. Enteritidis/mL. Results revealed that ENR reduced bacterial counts in the liver and spleen on days 3, 5, and 7 post-challenge more (P < 0.05) than any other treatments. However, bacterial counts in cecal contents among ENR, TBA, and CCA were similar at 5 and 7 D post-challenge but lower than those of PC. Additionally, the bacterial counts in liver, spleen, and cecum contents in TBA were lower (P < 0.05) than in PC at 3, 5, and 7 D post-challenge; the bacterial counts in spleen contents in TBA were lower (P < 0.05) than in CCA at 7 D post-challenge. Tumor necrosis factor-α contents in TBA and CCA were lower (P < 0.05) than those in PC. Also, the ratio of villus height to crypt depth in the ileum of CCA was higher (P < 0.05) than that of PC and ENR; however, there was no difference in the secretory IgA content of the jejunum among the groups. In conclusion, EOA had a bacteriostatic effect on S. Enteritidis, and the effect of the thymol-benzoic acid complex surpassed that of the cinnamaldehyde-caproic acid complex. Therefore, EOA may act as an effective antibiotic substitute for animals in the prevention and treatment of Salmonella.

中文翻译:

精油和有机酸的日粮组合可减少受感染雏鸡的肠炎沙门氏菌。

本研究旨在确定精油和有机酸 (EOA) 对肠炎沙门氏菌 (S. Enteritidis) 攻击的鸡的影响。1 日龄无特定病原体 (SPF) 雏鸡 (250) 被随机分配到 5 组,每组 50 只鸡。治疗组如下:1)基础饮食,阴性对照组(NC);2)基础饮食+肠炎沙门氏菌,阳性对照组(PC);3)PC+4000克/吨恩诺沙星(5%),抗生素组(ENR);4) PC + 800 g/t EOA1、百里酚-苯甲酸基团(TBA);5) PC + 800 g/t EOA2,肉桂醛-己酸基团 (CCA)。在 7 日龄时,除了北卡罗来纳州的鸡外,每只鸡都用 0.4 mL 的 4.4 × 109 cfu S. Enteritidis/mL 的悬浮液进行口服管饲。结果显示,ENR 在第 3、5 天减少了肝脏和脾脏中的细菌数量,和 7 比任何其他处理更多的攻击后 (P < 0.05)。然而,ENR、TBA 和 CCA 盲肠内容物中的细菌计数在攻击后 5 天和 7 天相似,但低于 PC。此外,在攻击后 3、5 和 7 天,TBA 中肝脏、脾脏和盲肠内容物的细菌计数低于 PC(P < 0.05);在攻击后 7 天,TBA 中脾脏内容物中的细菌计数低于(P < 0.05)CCA。TBA和CCA中肿瘤坏死因子-α含量低于PC(P < 0.05)。此外,CCA回肠绒毛高度与隐窝深度的比值高于PC和ENR(P < 0.05);然而,各组间空肠分泌IgA含量没有差异。总之,EOA 对肠炎沙门氏菌具有抑菌作用,百里酚-苯甲酸复合物的效果优于肉桂醛-己酸复合物。因此,EOA可作为动物预防和治疗沙门氏菌的有效抗生素替代品。
更新日期:2020-04-17
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