The objective of this study was to assess the effect of dietary yeast products on broiler chickens challenged with salmonella lipopolysaccharide (LPS). The chicks were divided into 8 treatments with 6 replicates and 9 birds per replicate. The treatments consisted of a positive control (PC) [without supplementation and not challenged]; negative control (NC) [without supplementation but challenged]; whole yeast and challenged; yeast cell wall and challenged; yeast glucan and challenged; yeast mannan and challenged; zinc bacitracin and challenged; and Salinomycin and challenged. Whole yeast or Yeast cell wall was included at 2.0 g/kg diet. Yeast glucan or mannan was added at 0.20 g/kg diet. Zinc bacitracin (ZNB) and Salinomycin (SAL) was included at 50 and 60 ppm, respectively. Dietary treatments had no effect (P > 0.05) on feed intake (FI) at day 10. Supplementation with yeast and its derivatives improved (P < 0.05) body weight gain (BWG) and feed conversion ratio (FCR) on day 10. On days 24 and 35, LPS challenge declined FI, BWG, FCR, and flock uniformity (day 28) in the NC group compared to the PC group. Yeast products and antibiotics improved (P < 0.05) FI, BWG, FCR, and flock uniformity in LPS-challenged birds. On day 24, spleen weight increased while bursa weight decreased in the NC group relative to the PC group; this effect was reversed (P < 0.05) by feeding all yeasts and antibiotics. On day 24, application of all the dietary treatments ameliorated the changes observed in white blood cell, lymphocyte and monocyte counts as well as albumin and immunoglobulin G of NC birds. On day 35, all yeasts additives, ZNB and SAL improved (P < 0.05) the meat yield of broilers challenged with LPS. In conclusion, supplementation of diets with yeast and its derivatives can ameliorate the negative effects of salmonella LPS challenge on broiler chicks, thus improving the performance, flock uniformity, and meat yield.

中文翻译：

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自溶全酵母和酵母成分对沙门氏菌脂多糖激发的肉鸡的影响。

这项研究的目的是评估饮食酵母产品对沙门氏菌脂多糖（LPS）攻击的肉鸡的影响。将小鸡分为8个处理，每组6个重复，每个重复9个鸡。治疗包括阳性对照（PC）[不补充且不受挑战]；阴性对照（无补充但有挑战性）；整个酵母和挑战；酵母细胞壁并受到挑战；酵母葡聚糖和挑战; 酵母甘露聚糖和挑战；杆菌肽锌和挑战; 和沙利霉素并受到挑战。以2.0 g / kg的饮食摄入全酵母或酵母细胞壁。以0.20 g / kg的饮食添加酵母葡聚糖或甘露聚糖。杆菌肽锌（ZNB）和盐霉素（SAL）的含量分别为50和60 ppm。饮食疗法没有效果（P> 0。05）在第10天时采食量（FI）。在第10天时，酵母及其衍生物的添加改善（P <0.05）体重增加（BWG）和饲料转化率（FCR）。在第24天和第35天，LPS攻击减少与PC组相比，NC组的FI，BWG，FCR和鸡群均匀性（第28天）。酵母产品和抗生素改善了LPS感染鸟类的FI，BWG，FCR和鸡群均匀性。在第24天，相对于PC组，NC组的脾脏重量增加，而滑囊重量减少。通过喂食所有酵母菌和抗生素可逆转这种影响（P <0.05）。在第24天，所有饮食处理的应用改善了NC禽的白细胞，淋巴细胞和单核细胞计数以及白蛋白和免疫球蛋白G的变化。在第35天，所有酵母添加剂ZNB和SAL均得到改善（P <0。05）用LPS攻击的肉鸡的肉产量。总之，在日粮中添加酵母及其衍生物可以减轻沙门氏菌LPS攻击对肉鸡的负面影响，从而提高生产性能，鸡群均匀度和肉产量。