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Recent Progress in the Biological Applications of Reactive Oxygen Species-Responsive Polymers
Polymer Reviews ( IF 13.1 ) Pub Date : 2019-07-23 , DOI: 10.1080/15583724.2019.1641515
Zhiyuan Fan 1 , Huaping Xu 1
Affiliation  

Responsive polymeric materials that are sensitive to biological stimuli including temperature, pH, enzymes, or redox conditions have attracted research interest in recent years. Among these, reactive oxygen species (ROS)-responsive polymers are particularly appealing because of the special role of ROS in living organisms. ROS are the indicator and cause of certain diseases, and they are also important signaling molecules. ROS-responsive polymers could possess the following functions: drug carriers, ROS probes, or medications for certain ROS-related diseases. In this review, we analyze the progress about ROS-responsive polymers made in recent years and predict the future trends of ROS-responsive polymers from the above mentioned perspectives. Due to the limited scope of this review, some older articles are not covered here and are left for more comprehensive reviews.

中文翻译:

活性氧反应敏感型聚合物在生物应用中的最新进展

对生物刺激包括温度,pH,酶或氧化还原条件敏感的响应性聚合物材料近年来引起了研究兴趣。其中,活性氧(ROS)响应型聚合物特别有吸引力,因为ROS在活生物体中具有特殊作用。ROS是某些疾病的指标和病因,它们也是重要的信号分子。ROS响应性聚合物可能具有以下功能:药物载体,ROS探针或某些与ROS相关的疾病的药物。在这篇综述中,我们分析了近年来有关ROS响应聚合物的进展,并从上述观点预测了ROS响应聚合物的未来趋势。由于本次审查的范围有限,
更新日期:2019-10-25
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