Abnormalities in the cardiac sympathetic nervous system have been documented in various heart diseases and have been directly implicated in their pathogenesis and disease progression. Noninvasive techniques using single-photon-emitting radiotracers for planar scintigraphy and single-photon emission computed tomography, and positron-emitting tracers for positron emissions tomography, have been used to characterize the cardiac sympathetic nervous system with norepinephrine analogs [123I] meta -iodobenzylguanidine for planar and single-photon emission computed tomography imaging and [11C] meta -hydroxyephedrine for positron emissions tomography. Their usefulness in prognostication and risk stratification for cardiac events has been demonstrated. This review bridges basic and clinical research and focuses on applying an understanding of tracer kinetics and neuronal biology, to aid in the interpretation of nuclear imaging of cardiac sympathetic innervation.

中文翻译：

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心脏交感神经系统的核成像

心力衰竭的特定疾病解释

心脏交感神经系统异常已在多种心脏病中得到记录，并直接与它们的发病机理和疾病进展有关。使用单光发射放射性示踪剂进行平面闪烁显像和单光子发射计算机体层摄影术以及正电子发射示踪剂进行正电子发射断层显像术的非侵入性技术已被用于通过去甲肾上腺素类似物[123I]的间碘碘苄胍表征心脏交感神经系统。平面和单光子发射计算机断层扫描成像和[11C]间羟基麻黄碱用于正电子发射断层扫描。已经证明了它们在心脏事件的预后和危险分层中的有用性。