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The risk of liver cancer in autoimmune liver diseases
Therapeutic Advances in Medical Oncology ( IF 4.9 ) Pub Date : 2019-07-12 , DOI: 10.1177/1758835919861914 Ana Lleo 1 , Ynto S. de Boer 2 , Rodrigo Liberal 3 , Massimo Colombo 4
Therapeutic Advances in Medical Oncology ( IF 4.9 ) Pub Date : 2019-07-12 , DOI: 10.1177/1758835919861914 Ana Lleo 1 , Ynto S. de Boer 2 , Rodrigo Liberal 3 , Massimo Colombo 4
Affiliation
According to Global Disease Burden, in 2015 there were 854,000 incident cases of liver cancer and 810,000 deaths globally, contributing to 20,578,000 disability-adjusted life-years (DALYs).1 Liver cancer stands as the fourth leading cause of cancer death after lung, colorectal, and stomach cancer and, in the last three decades, its incidence has increased by 75%. Interestingly, half of cases can be explained by changing population age structures, one-third by population growth, and less than 10% by changing age-specific incidence rates. While chronic infection with hepatitis B virus accounted for one-third of liver cancer deaths, alcohol was implicated in another 30%, hepatitis C in 21%, and other causes in 16%.
中文翻译:
自身免疫性肝病患肝癌的风险
根据全球疾病负担报告,2015年全球有85.4万例肝癌事件病例和810,000例死亡,为20,578,000例伤残调整生命年(DALYs)做出了贡献。1肝癌是仅次于肺癌,大肠癌和胃癌的第四大癌症死亡原因,在过去的三十年中,其发病率增加了75%。有趣的是,一半的病例可以通过改变人口年龄结构来解释,三分之一的人口可以通过人口增长来解释,不到10%的可以通过改变特定年龄的发病率来解释。乙型肝炎病毒的慢性感染占肝癌死亡人数的三分之一,另外30%涉及酒精,丙型肝炎占21%,其他原因占16%。
更新日期:2019-07-12
中文翻译:
自身免疫性肝病患肝癌的风险
根据全球疾病负担报告,2015年全球有85.4万例肝癌事件病例和810,000例死亡,为20,578,000例伤残调整生命年(DALYs)做出了贡献。1肝癌是仅次于肺癌,大肠癌和胃癌的第四大癌症死亡原因,在过去的三十年中,其发病率增加了75%。有趣的是,一半的病例可以通过改变人口年龄结构来解释,三分之一的人口可以通过人口增长来解释,不到10%的可以通过改变特定年龄的发病率来解释。乙型肝炎病毒的慢性感染占肝癌死亡人数的三分之一,另外30%涉及酒精,丙型肝炎占21%,其他原因占16%。