Current clinical issues in testicular germ cell tumour management include limited sensitivity and specificity of conventional biomarkers and, therefore, reliance on serial CT imaging in follow-up monitoring, as well as poor ability to risk stratify patients. Circulating microRNAs are likely to help overcome these challenges and, importantly, could offer cost savings to health-care systems.

中文翻译：

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循环微RNA能解决睾丸生殖细胞恶性肿瘤的临床难题吗？

睾丸生殖细胞肿瘤治疗的当前临床问题包括常规生物标志物的敏感性和特异性有限，因此，在随访监测中依赖于连续CT成像以及对患者进行分层风险的能力较弱。流通的microRNA可能有助于克服这些挑战，并且重要的是，可以节省医疗保健系统的成本。