Phylogenomic analyses have increasingly adopted species tree reconstruction using methods that account for gene tree discordance using pipelines that require both human effort and computational resources. As the number of available genomes continues to increase, a new problem is facing researchers. Once more species become available, they have to repeat the whole process from the beginning because updating species trees is currently not possible. However, the de novo inference can be prohibitively costly in human effort or machine time. In this paper, we introduce INSTRAL, a method that extends ASTRAL to enable phylogenetic placement. INSTRAL is designed to place a new species on an existing species tree after sequences from the new species have already been added to gene trees; thus, INSTRAL is complementary to existing placement methods that update gene trees.

中文翻译：

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INSTRAL：使用四重奏分数的不一致感知系统发育放置

系统发育分析越来越多地采用物种树重建，使用需要人力和计算资源的管道来解释基因树不一致的方法。随着可用基因组的数量不断增加，研究人员面临着一个新问题。一旦有更多物种可用，他们必须从头开始重复整个过程，因为目前无法更新物种树。然而，从头推理在人力或机器时间方面的成本可能高得令人望而却步。在本文中，我们介绍了 INSTRAL，这是一种扩展 ASTRAL 以实现系统发育定位的方法。INSTRAL 旨在将新物种的序列添加到基因树后，将新物种放置在现有物种树上；因此，