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The Avidity Game: Selecting Natural-Born Killers
Immunity ( IF 32.4 ) Pub Date : 2019-06-18 , DOI: 10.1016/j.immuni.2019.05.018
Christopher E. Andoniou , Iona S. Schuster , Mariapia A. Degli-Esposti

Natural killer (NK) cells display some features equivalent to those of adaptive immune effectors, but the molecular processes underlying these adaptive-like characteristics are just beginning to be defined. In this issue of Immunity, Adams et al. (2019) and Grassmann et al. (2019) report that avidity selection for Ly49H governs the expansion, differentiation, and function of NK cells after cytomegalovirus infection.



中文翻译:

Avidity游戏:选择天生的杀手

天然杀伤(NK)细胞显示出与适应性免疫效应子相同的某些特征,但是这些适应性样特征的分子过程才刚刚开始被定义。在本期《免疫》中,亚当斯(Adams)等人。(2019)和格拉斯曼(Grassmann)等人。(2019)报告说,在巨细胞病毒感染后,Ly49H的亲和力选择决定了NK细胞的扩增,分化和功能。

更新日期:2019-06-18
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