Fecal microbiota transplantation (FMT), the core therapy for remodeling the gut microbiota with a long medical history, has gained great attention worldwide in recent years. Increasing studies have explored its indications, methodology, efficacy, safety, and ethics. Purified forms of FMT, using an automated method for the purification of fecal microbiota from stool, has become a reality. Colonic transendoscopic enteral tubing makes frequent FMT delivery into the whole colon feasible. This review focuses on the recent progress in laboratory preparation, updated clinical strategies, novel delivery methods, and ethical issues surrounding FMT in clinical studies.

粪便微生物菌群移植（FMT）是重塑肠道微生物菌群的核心疗法，已有很长的医学历史，近年来在世界范围内引起了广泛关注。越来越多的研究探索了它的适应症，方法，功效，安全性和道德。使用自动方法从粪便中纯化粪便微生物群的FMT纯化形式已成为现实。结肠经内镜下肠管使频繁的FMT输送到整个结肠变得可行。这篇综述着重于实验室准备的最新进展，更新的临床策略，新颖的给药方法以及临床研究中围绕FMT的伦理问题。