With great interest we read the review article of Iacucci et al on advanced endoscopic techniques in IBD.1 The authors clearly recognise the current limitations of the different endoscopic scoring tools for disease activity in IBD and provide potential solutions with new advanced techniques. We fully agree that interobserver variability is problematic for treatment planning and IBD drug development and we lack objective definitions of endoscopic remission that predict further disease course in both Crohn’s disease and ulcerative colitis (UC). Scoring systems were mostly developed at the end of the previous century, based on evaluations with fiberoptic endoscopes or poor quality white light video-endoscopes. Intrinsically, it could be anticipated that by seeing more details and nuances such as with virtual chromo-endoscopy, this could result in a superior assessment of the disease activity in IBD. …

中文翻译：

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对 IBD 中的内窥镜疾病活动进行评分：人工智能比我们看到的更多更好

我们怀着极大的兴趣阅读了 Iacucci 等人关于 IBD 中先进内窥镜技术的评论文章。1 作者清楚地认识到当前用于 IBD 疾病活动的不同内窥镜评分工具的局限性，并提供了新的先进技术的潜在解决方案。我们完全同意，观察者间的差异对于治疗计划和 IBD 药物开发是有问题的，我们缺乏内镜缓解的客观定义，无法预测克罗恩病和溃疡性结肠炎 (UC) 的进一步病程。评分系统大多是在上世纪末开发的，基于对光纤内窥镜或劣质白光视频内窥镜的评估。从本质上讲，可以预期通过看到更多的细节和细微差别，例如虚拟色素内窥镜，这可能导致对 IBD 疾病活动性的更好评估。…