In this issue of Immunity, O'Koren et al. (2019) report that murine retinal microglia are long lived and are divided into two spatially and functionally distinct niches in the retina. In models of retinal neurodegeneration, retinal microglia migrate to the subretinal space, an inducible disease-associated niche, where they are neuroprotective.

中文翻译：

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可视化视网膜小胶质细胞的异质性。

在本期《免疫》中，O'Koren等人。（2019）报告说，鼠视网膜小胶质细胞寿命长，在视网膜上分为两个在空间和功能上不同的生态位。在视网膜神经变性模型中，视网膜小胶质细胞迁移到视网膜下间隙，这是一种可诱导的疾病相关的利基，具有神经保护作用。