We thank Blackwell et al 1 for raising an important question about the classification of depression in a population of IBD patients in the UK. In our study,examining depression as a risk factor for the development of IBD,2 we chose to use a more restrictive case definition of depression based closely on a definition of major depressive disorder (MDD) as a clinically significant form of depression recognised in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5)3 and known to be associated with a significant degree of morbidity and mortality.4 5 In …

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英国 IBD 人群中抑郁症编码的变化趋势：作者回复

我们感谢 Blackwell 等人 1 提出了一个关于英国 IBD 患者群体中抑郁症分类的重要问题。在我们的研究中，将抑郁症作为 IBD 发展的危险因素进行检查，2 我们选择使用更严格的抑郁症病例定义，该定义密切基于重度抑郁症 (MDD) 的定义，即抑郁症的临床显着形式。精神疾病诊断和统计手册 (DSM-5)3 并且已知与显着程度的发病率和死亡率相关。4 5 在……