Treating cocaine addiction is a major challenge and currently no FDA approved pharmacotherapies exist. One complicating factor is a high rate of comorbidity between cocaine and neuropsychiatric conditions such as anxiety. The relationship between anxiety symptoms and cocaine addiction is complicated; anxiety can be both a predisposing factor and a consequence of cocaine use as anxiety symptoms often emerge during drug use and withdrawal. Identifying and understanding the shared biological mechanisms that lead to comorbid anxiety and cocaine addiction, irrespective of which comes first, is critical for the identification of new treatments.

中文翻译：

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焦虑，成瘾的鸡蛋或鸡蛋：将G9a靶向治疗合并症和可卡因成瘾。

可卡因成瘾的治疗是一项重大挑战，目前尚无FDA批准的药物治疗方法。一个复杂的因素是可卡因与神经精神疾病（如焦虑症）之间的合并症发生率很高。焦虑症状与可卡因成瘾之间的关系很复杂。焦虑既可能是诱发因素，也可能是可卡因使用的结果，因为在吸毒和停药期间经常出现焦虑症状。识别和理解导致共病焦虑和可卡因成瘾的共同生物学机制，无论首先发生哪种机制，对于确定新的治疗方法都是至关重要的。