We focus on the most recent developments towards synthesis, modeling, and applications of molecular bottlebrushes. Unique structural characteristics and properties of the bottlebrushes along with an ability to synthetically tailor their structure and functionality open up a number of emergent applications of these polymer systems. The conformation and resulting properties of molecular bottlebrushes and multi-component assemblies encompassing bottlebrushes can be regulated via chemical nature of the backbone and side moieties of bottlebrushes, variation of the distance between grafting points of the side groups, and the degree of polymerization of the side chains. Herein, we highlight the most recent progress in relating the structure of the bottlebrushes with their properties and focus on a number of diverse emerging applications involving bottlebrushes in solvents, melts, and bottlebrushes conjugated with surfaces, interfaces, linear chains, or biomacromolecules. Among such applications are drug delivery and sensing applications, electronic and photonic materials and materials with strain-adaptive stiffening, thermal stabilization and enhancement of activity of enzymes conjugated with copolymer bottlebrushes, and surface modification for biomedical applications.

我们专注于分子瓶刷的合成，建模和应用的最新发展。牙刷的独特结构特征和特性，以及通过合成方式调整其结构和功能的能力，为这些聚合物系统的许多新兴应用打开了大门。可以通过骨架的化学性质和牙刷的侧基部分，侧基的接枝点之间的距离变化以及侧的聚合度来调节分子式牙刷和包含该牙刷的多组分组件的构象和所得特性。链。在此处，我们重点介绍了将牙刷的结构与其特性相关联的最新进展，并重点关注了许多新兴应用，包括溶剂，熔体中的牙刷以及与表面，界面，线性链或生物大分子共轭的牙刷。在这些应用中包括药物输送和传感应用，电子和光子材料以及具有应变适应性变硬，热稳定和增强与共聚物牙刷结合的酶活性的材料，以及用于生物医学应用的表面修饰。