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The role of incurred materials in method development and validation to account for food processing effects in food allergen analysis
Analytical and Bioanalytical Chemistry ( IF 4.3 ) Pub Date : 2019-02-13 , DOI: 10.1007/s00216-019-01642-3
Monica Mattarozzi , Maria Careri

The issue of undeclared allergens represents a matter of great concern, being the subject of many alert notifications by the Rapid Alert System for Food and Feed portal of the European Commission, often leading to food recalls. The availability of reliable analytical approaches able to detect and quantify hidden allergens in processed foods is increasingly requested by the food industry, food safety authorities and regulatory bodies to protect sensitive consumers’ health. The present review discusses the fundamental role of incurred materials for method development and analytical performance assessment in a metrology perspective on testing for undeclared allergens in processed foodstuffs. Due to the nature of the analytes and their susceptibility to various processing effects, reliability and comparability of results have posed a great challenge. In this context, the use of incurred samples as reference materials permits simulation of the effects of food processing on target analyte structure affecting analyte extractability and detectability.

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中文翻译:

诱变材料在方法开发和验证中的作用,以说明食品过敏原分析中的食品加工效果

未声明的过敏原问题是一个非常令人关注的问题,它是欧盟委员会食品和饲料快速警报系统门户网站发出的许多警报通知的主题,常常导致食品召回。食品行业,食品安全当局和监管机构越来越要求能够提供可靠的分析方法来检测和量化加工食品中的隐藏过敏原,以保护敏感消费者的健康。本综述从计量学角度探讨了加工方法中未申报的过敏原的检测方法中所用材料在方法开发和分析性能评估中的基本作用。由于分析物的性质及其对各种处理效果的敏感性,结果的可靠性和可比性提出了巨大的挑战。

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更新日期:2019-02-13
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