The field of dermatology has seen numerous therapeutic innovations in the past decade, with platelet-rich plasma recently garnering significant interest in acne scarring. This review consolidates the available evidence on platelet-rich plasma for the practicing dermatologist and evaluates the current evidence up to May 31, 2018. A search was conducted in the PubMed database for the terms platelet-rich plasma or platelet releasate or platelet gel or PRP and dermatology or skin or acne or scar or cutaneous, with 13 articles meeting the inclusion criteria. The quality of each individual study was evaluated, and levels of evidence were assigned according to the Centre for Evidence-Based Medicine, Oxford, United Kingdom. This review reveals that activated, leukocyte- and platelet-rich plasma in combination with fractional ablative laser treatment administered in 2 or 3 sequential sessions 1 month apart improves the appearance of acne scars. The evidence for the use of platelet-rich plasma with microneedling is less supportive. Because of the heterogeneity of the studies and widely variable outcome measures, comparison between platelet-rich plasma treatments and subsequent statistical analysis could not be performed. Although these studies use various subjective and objective evaluation methods, the addition of platelet-rich plasma provides improvements in acne scarring, higher patient satisfaction, and decreased postprocedure downtime.

在过去的十年中，皮肤病学领域已经看到了许多治疗方法的创新，其中富含血小板的血浆最近引起了人们对痤疮疤痕的浓厚兴趣。该评价为皮肤科医生提供了有关富含血小板血浆的现有证据的综合信息，并评估了截至2018年5月31日的最新证据。在PubMed数据库中搜索了术语“富含血小板血浆或血小板释放物或血小板凝胶或PRP”和皮肤病或皮肤或粉刺或疤痕或皮肤，其中13篇文章符合纳入标准。根据英国牛津的循证医学中心对每个研究的质量进行了评估，并确定了证据水平。这篇评论揭示了活化的，富含白细胞和血小板的血浆与间隔消融激光治疗相结合，相隔1个月分2或3次进行，可以改善痤疮疤痕的出现。将富含血小板的血浆与微针一起使用的证据支持较少。由于研究的异质性和广泛的结局指标，因此无法进行富血小板血浆治疗与随后的统计分析之间的比较。尽管这些研究使用了各种主观和客观评估方法，