Two previously undescribed oleanane-type triterpene saponins named liangwanosides III-IV, and one undescribed eudesmane glycoside named liangwanoside A were obtained from the leaves of Metapanax delavayi, a Chinese folk medicine especially for tea used in Yunnan, together with four known compounds. The structures of the undescribed compounds were determined by detailed spectroscopic (1D/2D NMR), HR-ESI-MS data analysis and chemical evidence. The activity against human benign prostate hyperplasia was evaluated with BPH-1 cell line. Most of the isolated compounds showed moderate inhibitory activity against BPH-1 cells at 100 and 50 μM in vitro.

中文翻译：

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Metapanax delavayi叶化学成分及其体外抗BHP活性

两种以前未描述的齐墩果烷型三萜皂苷（即凉瓜苷III-IV）和一种未描述的丁香苷（称为凉瓜苷A）是从云南特供茶的中草药Metapanax delavayi的叶子中获得的，以及四种已知化合物。未描述的化合物的结构通过详细光谱（1D/2D NMR）、HR-ESI-MS 数据分析和化学证据确定。用 BPH-1 细胞系评估对人良性前列腺增生的活性。大多数分离的化合物在 100 和 50 μM 体外对 BPH-1 细胞显示出中等抑制活性。