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Optimal Number of Heartbeats Required for Representing Left Chamber Volumes and Function in Patients with Rate-Controlled Atrial Fibrillation.
Journal of the American Society of Echocardiography ( IF 6.5 ) Pub Date : 2019-02-01 , DOI: 10.1016/j.echo.2018.12.004 Victor Chien-Chia Wu , Kyoko Otani , Chia-Hung Yang , Pao-Hsien Chu , Masaaki Takeuchi
Journal of the American Society of Echocardiography ( IF 6.5 ) Pub Date : 2019-02-01 , DOI: 10.1016/j.echo.2018.12.004 Victor Chien-Chia Wu , Kyoko Otani , Chia-Hung Yang , Pao-Hsien Chu , Masaaki Takeuchi
BACKGROUND
The optimal number of heartbeats required for representing left heart chamber function in patients with atrial fibrillation (AFib) has not been extensively studied.
METHODS
To determine the optimal number, we performed an automated quantification analysis of three-dimensional echocardiography (3DE) data sets in 93 patients with AFib for whom 10-20 consecutive one-beat full-volume 3DE data sets were acquired twice. We measured left ventricular end-diastolic volume (LVEDV), left ventricular ejection fraction (LVEF), and maximal left atrial volume (LAVmax) in each heartbeat; each parameter was averaged using a serial number of heartbeats randomly selected, and these values were compared with the averaged value obtained from the entire set of heartbeats. Coverage probability was determined using predefined cutoff values, the relative percentage differences in LVEDV and LAVmax of 5%, and the absolute percentage differences in LVEF of 5%. The optimal number of heartbeats was defined as the minimum number of heartbeats showing coverage probability ≥95%.
RESULTS
Out of 93 patients, 73 patients had acceptable left ventricular contour casts (feasibility, 78%), and 79 patients had acceptable left atrial contour casts (feasibility, 85%). Using the aforementioned criteria, the minimum optimal number of heartbeats was nine for LVEDV and six for LAVmax. The corresponding minimum optimal number of heartbeats for LVEF was eight. However, the results varied as a function of the size of the chamber, the left ventricular function, and whether the AFib ventricular rate was controlled.
CONCLUSIONS
In patients with AFib, the optimal number of heartbeats required to obtain representative chamber volumes and function was six to nine heartbeats randomly selected using 3DE automated quantification software.
中文翻译:
速率控制性心房颤动患者代表左室容积和功能所需的最佳心跳次数。
背景技术尚未广泛研究用于代表房颤患者(AFib)的左心室功能所需的最佳心跳数。方法为了确定最佳数目,我们对93例AFib患者进行了三维超声心动图(3DE)数据集的自动化定量分析,这些患者两次获得10-20个连续的一搏全量3DE数据集。我们测量了每次心跳时的左心室舒张末期容积(LVEDV),左心室射血分数(LVEF)和最大左心房容积(LAVmax)。使用随机选择的一系列心跳对每个参数取平均值,然后将这些值与从整个心跳集获得的平均值进行比较。使用预定义的临界值确定覆盖率,LVEDV和LAVmax的相对百分比差异为5%,LVEF的绝对百分比差异为5%。最佳心跳次数定义为显示覆盖概率≥95%的最小心跳次数。结果在93例患者中,有73例患者的左心室轮廓铸型可接受(可行性,78%),在79例患者中的左心室轮廓铸型可接受(可行性,85%)。使用上述标准,LVEDV的最小最佳心跳数为9,LAVmax的最小最佳心跳数为6。LVEF的相应最小最佳心跳数为8。但是,结果随室大小,左心室功能以及是否控制AFib心室率而变化。结论对于AFib患者,
更新日期:2019-02-01
中文翻译:
速率控制性心房颤动患者代表左室容积和功能所需的最佳心跳次数。
背景技术尚未广泛研究用于代表房颤患者(AFib)的左心室功能所需的最佳心跳数。方法为了确定最佳数目,我们对93例AFib患者进行了三维超声心动图(3DE)数据集的自动化定量分析,这些患者两次获得10-20个连续的一搏全量3DE数据集。我们测量了每次心跳时的左心室舒张末期容积(LVEDV),左心室射血分数(LVEF)和最大左心房容积(LAVmax)。使用随机选择的一系列心跳对每个参数取平均值,然后将这些值与从整个心跳集获得的平均值进行比较。使用预定义的临界值确定覆盖率,LVEDV和LAVmax的相对百分比差异为5%,LVEF的绝对百分比差异为5%。最佳心跳次数定义为显示覆盖概率≥95%的最小心跳次数。结果在93例患者中,有73例患者的左心室轮廓铸型可接受(可行性,78%),在79例患者中的左心室轮廓铸型可接受(可行性,85%)。使用上述标准,LVEDV的最小最佳心跳数为9,LAVmax的最小最佳心跳数为6。LVEF的相应最小最佳心跳数为8。但是,结果随室大小,左心室功能以及是否控制AFib心室率而变化。结论对于AFib患者,